The mission of the Stanford-SLAC Cryo-EM Center (S2C2) is to provide:
- Access to state-of-the-art instrumentation for specimen vitrification and cryo-EM data collection towards atomic resolution structure determination.
- Support in screening and optimization of vitrified samples.
- Training to enable scientists to become independent cryo-EM investigators.
Our Center has cryo-specimen preparation devices, data quality assessment tools for on-the-fly evaluation and visualization, and image data storage capacity. Our expert staff also train, assist and advise users, both on-site and remotely, and are available for consultation beforehand and for follow-up discussions. We cross-train scientists who want to employ cryo-EM within their own research portfolios. Our training - including short-term and long-term in-residence programs for single particle cryo-EM workflow, from specimen preparation to structure validation, is targeted at a wide variety of skill levels. Access to the Center is through an open process based on scientific merit.