photo of students from Puerto Rico using one of SLAC's cryo-electron microscopes

Mission Statement:

The missions of the Stanford-SLAC Cryo-EM Center (S2C2) are:

  1. to provide access to state-of-the-art cryo-EM instruments for data collection towards atomic resolution structure determination of biochemically purified single particles and
  2. to enable scientists across the nation to become independent cryo-EM investigators.

Our Center also has cryo-specimen preparation devices, data quality assessment tools for on-the-fly evaluation and visualization, and image data storage capacity on a short-term basis. We provide expert staff that trains, assists and advises users, both on-site and remotely, and are available for consultation beforehand and in a follow-up program. We cross-train scientists who want to employ cryo-EM within their own research portfolios. Our training is targeted at a wide variety of skill levels - including short-term and long-term in-residence training programs for single particle cryo-EM workflow from specimen preparation to structure validation. Access to the Center is through an open process based on scientific merit.

Read about S2C2 »Apply to use the cryo-EM facilities »Apply for cryo-EM training »

A National Center for Cryo-Electron Microscopy

S2C2 is co-located with the Stanford Synchrotron Radiation Lightsource and the Linac Coherent Light Source at SLAC National Accelerator Laboratory, Stanford University.


General Questions:

Proposals & Time Requests:

Lisa Dunn