The Stanford-SLAC CryoEM Center (S2C2) provides access to state-of-the-art cryoEM instruments for data collection towards atomic resolution structure determination of biochemically purified single particles and enables scientists across the nation to become independent cryoEM investigators.  The S2C2 is supported by the National Institutes of Health Common Fund Transformative High Resolution Cryo-Electron Microscopy program.

Project applications for S2C2 are due on the first day of each month and are generally reviewed within the same month. See User Access for more information.

SCSC is one of the four service centers of a National Network for CryoElectron Tomography, coordinated by a central network hub.  The service centers will specialize in cryoET specimen preparation.  The hub will perform cryoET data collection for all user laboratories served by the network, in addition to its service center functions.  The SCSC is supported by the National Institutes of Health Common Fund Microscopy Program.

The Dahlberg lab focuses on methodological development in the area of correlative light and electron microscopy. Separately, electron tomography and fluorescence microscopy have emerged as powerful methods for observing subcellular organization and biomolecular function in situ. However, each approach has strengths and weakness that are often complementary. Combining the two into one correlative approach keeps the best of both techniques while mitigating the weaknesses. 

Check out the website to learn more about the research and the lab members at the forefront of this exciting space.

Research in the Chiu lab includes methodology improvements in single particle cryoEM for atomic resolution structure determination of molecules and molecular machines, as well as in cryoET of cells and organelles towards subnanometer resolutions.

We collaborate with many researchers in and outside of the Stanford community on understanding biological processes such as protein folding, ion transports, RNA folds, virus assembly and disassembly, pathogen-host interactions, and neurodegenerations.