Find Out More About Stanford-SLAC Cryo-EM

The Cryo-EM (cryogenic electron microscopy) facility at SLAC, built and operated in partnership with Stanford University, is equipped with multiple state-of-the-art instruments for cryo-EM, a groundbreaking technology whose rapid development over the past few years has given scientists unprecedented views of the inner workings of the cell. Our facility is funded by different sources which have different restrictions to users and associated costs.

What is Cryo-Em?   

Our Programs

photo of students using cryo-EM

Stanford-SLAC Cryo-EM Center (S2C2)

The Stanford-SLAC Cryo-EM Center (S2C2) provides access to state-of-the-art cryo-EM instruments for data collection towards atomic resolution structure determination of biochemically purified single particles and enables scientists across the nation to become independent cryo-EM investigators.  The S2C2 is supported by the National Institutes of Health Common Fund Transformative High Resolution Cryo-Electron Microscopy program.

Stanford-SLAC CryoET Specimen Preparation Center (SCSC)

SCSC is one of the four service centers of a National Network for CryoElectron Tomography, coordinated by a central network hub.  The service centers will specialize in cryoET specimen preparation.  The hub will perform cryoET data collection for all user laboratories served by the network, in addition to its service center functions.  The SCSC is supported by the National Institutes of Health Common Fund Microscopy Program.

National Center for Macromolecular Imaging (NCMI)

A national center for 3-D electron microscopy from macromolecules to whole cells focused on cryo-EM technology research development and technology dissemination.  Collaborators from academia and industries are welcome to drive our research and training missions.  NCMI is supported by National Institute of General Medical Sciences (NIGMS) Biomedical Technology Research Resource.


Regional Cryo-EM Consortium

Funded by the National Institutes of Health (NIH) to establish and maintain ahigh resolution cryo-EM data collection facility. The facility is available only to consortium members, who are structural biologists specializing in cryo-EM techniques and who do not have high resolution data collection facilities at their home institutions. New consortium members must be approved by existing members and NIH. Regional Consortia for High-Resolution Cryoelectron Microscopy.